Composition of diesel exhaust varies with engine loading, producing differential health impact characteristics from the emissions

As noted in several prior posts, the study of the impact on diesel exhaust has focused on the PM10 and PM 2.5 profiles of the emissions. Recently, researchers argued that this view is too simplistic, and present an interesting study in support of their view. The researchers analyzed the composition...

What drives developmental defects in children exposed to drugs and alcohol as fetuses? Loss of chromosomes in brain cells?

Prenatal exposure to amphetamines and alcohol produces abnormal numbers of chromosomes in fetal mouse brains. The findings suggest these abnormal counts may contribute to the developmental defects seen in children exposed to drugs and alcohol in utero. Researchers injected pregnant mice with alcohol...

The temperature of the test environment impacts the results derived from laboratory mice

Only one drug in ten that holds the potential for being useful in humans because of the results of tests with mice proves to so be. One obvious reason is that mice are not humans even though we are both mammals. Another reason is less obvious. Human patients can be afforded, if they wish and have the...

Coyotes May Be Indirectly Responsible for Spreading Lyme Disease

Deer often are blamed for the spread of tick-borne Lyme disease; many local programs focus on deer populations as a method to control Lyme disease. A new thesis suggests these programs are not targeting the actual driving force, coyotes. Researchers note that records from the past three decades link...

Are animal models a good analogy for humans? A recently published study of mice suggests that there may be problems

To set standards, animal models are frequently used. Such use allows researchers to investigate disease and injury states in ways which would be considered unethical to inflict on humans. For example, to determine some threshold injury or disease state, various groups of animals may be exposed to widely...